Six patients underwent molecular testing on tumor DNA: two carried marked IC2-LoM [14,15], two exhibited loss of heterozygosity (LOH) at chromosome 11p15 [16,17], one carried somatic pathogenic variants of CTNNB1 and GNAS genes [13], and one carried somatic pathogenic variants of the MKRN3 and CYP17A1 genes [13]. This evidence concerns the gene MKRN3 and neoplasm.