EBF1 and leukemia: Another relevant fact among Ph+ leukemias is the IKZF1 deletions and other cooperative alterations in genes related to B-cell differentiation such as PAX5, CDKN2A/B and EBF1, in addition to other genes such as BTG1, RB1, EBF1, MEF2C, RUNX1, SLX4IP, HBS1L, TSC22D1, FOXP1, LEF1, ETV6, TCF3 and TCF4 [62].