PSIP1 and cancer: A recent pan-cancer bioinformatics study by Zhang et al. [51] revealed that LEDGF/p75 transcript and protein expression are differentially regulated in multiple primary cancers, with increased expression in some tumors (e.g., head and neck squamous cell carcinoma, [HNSC], and thymoma) and downregulation in others (e.g., BCa and PCa), and some cancers showing opposite expression of transcript and protein levels in the same tumor type.