Gene-to-gene analyses of RGN expression compared with that of keratin 18 (KRT18), Cadherin 2 (CDH2), Cadherin 1 (CDH1) and Vimentin (VIM) in primary and metastatic PCa cases were carried out in the Glinsky et al. [52], Grasso et al. [53], Lapointe et al. [54], Taylor et al. [55], TCGA [56], Tomlins et al. [57] and Varambally et al. [58] patient datasets (Figure 9). This evidence concerns the gene CDH2 and posterior cortical atrophy.