Albumin ≥ 3.5 g/L (HR: 0.189, 95% CI: 0.07–0.47, p < 0.001) was associated with lower risk for HT. Figure 6 summarizes the main variables identified in univariate analysis able to predict OS, PFS and HT to HGBCL. This evidence concerns the gene ALB and hematocrit.