KRAS and colorectal carcinoma: Patients with young-onset CRC (≤50 years old) had lower rates of TP53 (71.4% versus 75%, p = 1), APC (66.7 versus 91.7%, p = 0.2), and KRAS (38.1% versus 50%, p < 0.7) compared to patients over 50 years of age, but this was not statistically significant (Table 3).