CD4 and tuberculosis: Currently, LAM assay is only recommended for testing in PLHIV with low CD4 counts and report limited sensitivity in the wider population, but newer generation assays are under evaluation, including a third-generation Fujifilm SILVAMP TB LAM II (FujiLAM) which is expected to have much improved sensitivity and could potentially be used amongst people with TB who do not have HIV [78, 82].