In the absence of IFN-β1a pre-treatment, HRV 16 infection led to significantly lower expression of FOXJ-1 after 24 h and 48 h when compared to pre-treated cells (mRNA-Expression FOXJ-1, log2(fold change), 24 h: -IFN-β1a/ + HRV -1.53 ± 1.29 vs. + IFN-β1a/ + HRV 0.18 ± 0.70, p = 0.0015; 48 h: -IFN-β1a/ + HRV -0.67 ± 0.79 vs. + IFN-β1a/ + HRV 0.73 ± 0.41, p = 0.0125) (Fig. 3c). This evidence concerns the gene IFNA1 and infection.