CAR T cell-mediated production of IFN-γ with target antigen-positive non-Ph-like and Ph-like ALL cell line (eg, CD19+/TSLPR- NALM-6, CD19+/TSLPR+MUTZ5, CD19+/TSLPR- TVA-1 [49]) co-incubation was also analogously suppressed in the presence of concomitant dasatinib or ruxolitinib compared to no TKI exposure (Supplementary Fig. 7C). This evidence concerns the gene CRLF2 and acute lymphoblastic leukemia.