As delineated in Fig 2A, genes within the black module (n = 75) were predominantly enriched in several pathways, including Oligodendrocyte Specification and Differentiation, yielding Myelin Components for the Central Nervous System (CNS) (WP4304), Molecular Mechanisms of SARS-CoV-2 and Angiotensin-Converting Enzyme 2 Receptor (WP4883), Glial Cell Differentiation (WP2276), and MECP2 and Associated Rett Syndrome (WP3584), among others. The gene discussed is MECP2; the disease is atypical Rett syndrome.