GLS and non-small cell lung carcinoma: Glutamine serves multiple roles in cellular metabolism, and glutaminase (GLS1)‐mediated hydrolysis not only provides energy and reducing equivalents but also supplies metabolic intermediates as biosynthetic precursors for the synthesis of non‐essential amino acids, nucleotides, and fatty acids.[10] Consequently, we contemplated developing therapeutics targeting glutamine metabolism to refine the treatment strategy for Osimertinib‐resistant NSCLC.