As depicted in Supplemental Figures 3 and 4, the Evi1-overexpressed recipient mice developed a similar MDS/MPN–like disease characterized by decreased lymphocyte (LY), RBC, hemoglobin, and platelet counts in PB, along with an increased neutrophil (NE) count (Supplemental Figure 3, B–G). This evidence concerns the gene RUNX1 and myelodysplastic syndrome.