MECOM and myeloproliferative disorder: As depicted in Supplemental Figures 3 and 4, the Evi1-overexpressed recipient mice developed a similar MDS/MPN–like disease characterized by decreased lymphocyte (LY), RBC, hemoglobin, and platelet counts in PB, along with an increased neutrophil (NE) count (Supplemental Figure 3, B–G).