TIMM50 and cardiac hypertrophy: Additionally, TIMM50, the mammalian homologue of Tim50, was shown to be involved in steroidogenesis and plays a preventive role in pathological cardiac hypertrophy and several types of cancer (Bose et al., 2019; Tang et al., 2017; Sankala et al., 2011; Gao et al., 2016; Zhang et al., 2019).