In patients with T2DM, risks of cardiovascular mortality and heart failure (HF) increased with decreasing kidney function (based on eGFR) and increasing albuminuria (based on urine albumin-to-creatinine ratio [UACR]).In patients with high urine albumin creatine ratio, adding Finerenone reduced this ratio by reducing albuminuria in diabetic nephropathy patients [42]. The gene discussed is ALB; the disease is diabetic kidney disease.