Our study included 28 subjects with unilateral or bilateral abnormal GIN (70%; 17 with CANS stroke), 19 with abnormal PPP (47.5%; 16 with CANS stroke), 17 with abnormal APP (42.5%; 10 with CANS stroke), and 5 with abnormal SP (12.5%; 2 with CANS stroke). The gene discussed is APP; the disease is stroke disorder.