Due to the albumin-binding properties of OxFol-1, blood retention was high (9.9‒12% ID/g at 4 h p.i.)and the accumulation in KB tumor xenografts increasing over time (22‒28% ID/g at 4 h p.i. and 28–31% ID/g at 24 h p.i.). Here, ALB is linked to neoplasm.