All four N-linked glycosylation sites—N338, N1378, and N1392—on NaV1.1 were affected by seven mutations—S340F (Depienne et al., 2009), S340P (Depienne et al., 2009), S340Y (Landrum et al., 2020), N1378H (Zuberi et al., 2011), N1378T (Zuberi et al., 2011), H1393P (Stefanaki et al., 2006), T1394I (Zuberi et al., 2011)—in Dravet syndrome patients. The gene discussed is SCN1A; the disease is Dravet syndrome.