SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: All four N-linked glycosylation sites—N338, N1378, and N1392—on NaV1.1 were affected by seven mutations—S340F (Depienne et al., 2009), S340P (Depienne et al., 2009), S340Y (Landrum et al., 2020), N1378H (Zuberi et al., 2011), N1378T (Zuberi et al., 2011), H1393P (Stefanaki et al., 2006), T1394I (Zuberi et al., 2011)—in Dravet syndrome patients.