Notably, the third cytoplasmic loop of DRD4 encodes a VNTR tract comprising a 16‐amino acid segment, with 2–11 repeat variants.[39] To investigate whether DRD4 promotes CRC metastasis through the variant VNTR, we produced DRD4‐overexpressing vectors with two or four VNTR repeats (Figure4A). This evidence concerns the gene DRD4 and colorectal carcinoma.