We found that treatment with IKE massively inhibited tumor growth and enhanced tumor lipid peroxidation in mice bearing Parkin‐knockout xenograft tumors compared with that in mice bearing Parkin‐WT, and Lipro‐1 treatment obviously inhibited the effect of IKE (Figure5A–C; Figure S6A–C, Supporting Information). This evidence concerns the gene PRKN and neoplasm.