SLCO2A1 and cancer: Other diseases that can cause bowel strictures are listed in Table 1 and include immune-mediated and connective tissue disorders (eg, systemic lupus erythematosus,10 vasculitis,11 and sarcoidosis4), Cryptogenic Multifocal Ulcerous Stenosing Enteritis12 (CMUSE), monogenic disorders such as SLCO2A1-related disease,13 ischemic colitis,14 Non-Steroidal Anti-Inflammatory Drug (NSAID)-induced colopathy, complicated diverticular disease,14,15 radiation therapy,15 and endometriosis.16 Finally, malignancy should always be considered, especially in elderly patients or those with a history of cancer.