Strikingly, it gets more interesting to mention that akin to oncogenic miR-132, miR-212 in breast cancer (Xie M. et al., 2018), tumour promotor miR-29a in CRC (Shi et al., 2020), miR-21 mediated upregulation of P-gp in prostate cancer is a PTEN phosphatase-dependent circumstance. Here, PGP is linked to Familial prostate cancer.