This disrupts SMAD binding to EMT gene promoter regions.[69] Furthermore, cyclooxygenase‐2 (COX‐2), a target of aspirin,[70] has been associated with TGF‐β1‐induced EMT in bladder transitional cell carcinoma and was shown to mediate EMT in human breast cancer cells via the TGFβ/SMAD3 pathway.[71] In 2022, Feiyue et al.[72] found that aspirin‐soaked intraocular lenses could suppress the migration of SRA01/04 cells by continuously releasing aspirin in an in vitro lens capsule model. The gene discussed is TGFB1; the disease is breast cancer.