NLRP3 and periodontal disorder: Reactive oxygen species (ROS) are a determining factor in NLRP3 activation and certain research has demonstrated the role of oxidative stress (OS) in the pathogenesis of periodontal disease and periodontal tissue damage, as well as the beneficial role of antioxidant therapies (Sczepanik et al., 2020 2000; Liu et al., 2020; López-Valverde et al., 2024).