CAPN3 and neuromuscular disease caused by qualitative or quantitative defects of dysferlin: This study shows that dysferlinopathy and calpainopathy are frequently occurring LGMD-R subtypes in the enrolled population (DYSF-associated LGMD-R2: 69/261 [26.44%] and CAPN3-associated LGMD-R1:61/261 [23.37%]).