Neurofibromatosis (NF1 and NF2 genes) is reported as one of the main causes of single-gene disorders associated with ASD (Genovese and Butler, 2023), along with tuberous sclerosis, X-linked Rett syndrome (MECP2 gene), and fragile X syndrome (FMR1 gene). This evidence concerns the gene MECP2 and fragile X syndrome.