It relies on several proteins including BRCA1 and BRCA2, proteins of the Mre11-Rad50- Nbs1 (MRN) complex, CtIP, MRE11, RAD51, ATM, H2AX, PALB2, RPA, RAD52, and the Fanconi anemia pathway proteins (Vergote et al., 2022). Here, MRE11 is linked to anemia (phenotype).