We found eleven AD GWAS genes (ALCAM, APP, COX7C, EGFR, GPC6, MYO15A, PLCG2, RTN1, SEC61G, SORL1, and TMEM106B) to be differentially expressed between the ancestries in the iOPC cluster (Fig. 3A, Table 3). The gene discussed is SEC61G; the disease is Alzheimer disease.