Finally, SII (OR = 1.004, 95% CI: 1.001−1.006, P = 0.002) and serum creatinine (OR = 1.146, 95% CI: 1.069−1.228, P<0.001) were independently risk factors for the occurrence of DN, while age (OR = 0.920, 95% CI: 0.863−0.981, P = 0.011) and serum albumin (OR = 0.708, 95% CI: 0.595−0.844, P<0.001) were protective factors for the occurrence of DN (Table 2). The gene discussed is ALB; the disease is liver dysplastic nodule.