During inflammation, cytokines are released and they upregulate GLUT-1 on activated inflammatory cells.6This enhances the uptake of [18F]FDG during infection and inflammation, therefore can aid in assessment of sarcoidosis, tuberculosis, occult infection, autoimmune fibrosis, pneumonia, cystic fibrosis, and acute respiratory distress syndrome.7 Here, SLC2A1 is linked to sarcoidosis.