Oral contraceptive pills (OCPs) play a crucial role in the management of menstrual irregularities and infertility in women with PCOS. While studies show that GLP-1 RA use can lead to regular menstrual cycles, the exact mechanism or pathophysiology of these effects is not quite understood, emphasizing the need for randomized controlled trials specific to menstrual regularities. This evidence concerns the gene GLP1R and polycystic ovary syndrome.