Further examination of the TME utilizing flow cytometry disclosed that PHA-793887 markedly augmented the secretion of cytotoxic T cell-associated cytokines, including interferon-gamma (IFN-γ), tumor necrosis factor-alpha (TNF-α), and granzyme B (GZMB), within the tumor milieu (Figure 6F). The gene discussed is GZMB; the disease is neoplasm.