ESR1 and ductal breast carcinoma in situ: Base case: Whole DCIS cohort, 10 year time horizon. Simulation based on SEER data.Strategy A: Standard surgical intervention (BCS ± RT) for all womenvsStrategy B: Women with ER+, Grade I/II DCIS (50% of whole cohort) undergo AS; remaining undergo standard surgical intervention (BCS ± RT)