LOX and breast cancer: High expression; Associated with poor prognosis; ATP7A promotes the development and metastasis of breast cancer by maintaining and increasing LOX activity, regulating copper ion and ROS homeostasis, and increasing cisplatin resistance in breast cancer and helping breast cancer immune escape. Downregulation of ATP7A induces cuproptosis in breast cancer by promoting copper ion accumulation [22, 23, 24, 25, 26].