It is evident that the promoters of KLF3 and KLF6 were linked to more active enhancers in normal T cells, whereas promoters of T‐ALL specific TF genes (e.g., TCF12, TCF3, ETS2, and IKZF2) were associated with more active enhancers in T‐ALL cells (Figure 4F; Figure S4). This evidence concerns the gene IKZF2 and acute lymphoblastic leukemia.