ITGB3BP and cancer: By modulating the function of ITGB3, ITGB3BP affects crucial cellular activities, including wound healing, tissue regeneration, and immune responses.52,53 ITGB3BP participates bilaterally in cancer development, functioning as a tumor suppressor or promoter.54 Hence, it is central to the cell adhesion network and signaling pathways, critically mediating cellular functions essential for development, homeostasis, and disease progression.