Naples prognostic score (NPS), calculated from serum albumin, cholesterol, NLR and LMR, was initially carried out in the research of colorectal cancer by Galizia et al [23], recently has been widely researched in patients with malignancies, such as colorectal cancer, pancreatic cancer, endometrial cancer, lung cancer, gastric cancer, and esophageal squamous cell carcinoma. The gene discussed is ALB; the disease is colorectal cancer.