SLC38A7 and malignant colon neoplasm: In our previous study, we analyzed the gene expression and metabolic remodeling process of colon cancer cells after targeted inhibition of PHGDH by gene transcriptomics and metabolomics and found that amino acid transporters, amino acid metabolism, lipid synthesis-related pathways compensation, and other processes are involved in the response process after PHGDH inhibition [18].