FZD7 and intestinal cancer: In this context, FZD7 is particularlyrelevant in intestinal cancer,22−25 breast cancer,26−28 and ovarian cancer.29 The considerable interest toward FZD7 due to its role in cancer in combination with a recent increasein structural information for FZDs has put rational drug design ofFZD7 inhibitors at the forefront.5 In silico docking campaigns have resulted in compounds with apparentbiological activity.