In an unadjusted analysis, age, history of ischemic heart disease, NT-proBNP and eGFR <60 mmol/min/1.73 m2 were all associated with an elevated cardiac troponin concentration (≥5 ng/L) in both the restrictive spirometric pattern and normal lung function groups (Table 2). This evidence concerns the gene NPPB and coronary artery disorder.