When TF protein levels in AD, PD, and CN patients were plotted based on their age at the time of death, simple linear regression analysis indicated that the variation in cortical abundance of TF protein is not significantly associated with age in CN (TF in CN vs. Age: Slope: 0.5574, p-value = 0.2343, R-squared = 0.09289) individuals but is significantly associated with age in AD (TF in AD vs. Age: Slope: 1.056, p-value = 0.0121, R-squared = 0.08428) and PD (TF in PD vs. Age: Slope: -3.012, p-value <0.0001, R-squared = 0.5757) patients (Figures 7C–E). The gene discussed is TF; the disease is Alzheimer disease.