Plotting TF and TFRC protein levels in CN, AD, and PD individuals with PMI followed by simple linear regression analysis (Supplementary Figures S3A–F) indicated that the variation in cortical TF with PMI is not significantly associated in CN individuals (TF in CN vs. PMI: Slope: 0.1971, p-value = 0.7659, R-squared = 0.006094; Supplementary Figure S3A), AD (TF in AD vs. PMI: Slope: -0.7688, p-value = 0.1545, R-squared = 0.02796; Supplementary Figure S3B) and PD (TF in PD vs. PMI: Slope: -0.0725, p-value = 0.9248, R-squared = 0.0003639; Supplementary Figure S3C) patients. This evidence concerns the gene TFRC and Alzheimer disease.