IFNG and neoplasm: BRCAness could be significantly positively associated with the enrichment of immune-related signatures, such as those for IFNG response (rho=0.38, p=0.004) and T-cell inflamed tumor microenvironment (rho=0.46, p=0.0014), even to a larger extent with high tumor mutational burden (p<0.001) and high neoantigen load (p<0.001) (Figures 2A, B).