When comparing the estimated immune cell infiltrates in these cancer samples with BRCAness cancers without immune type (noBRIT), we found that not only cytotoxic T lymphocytes such as CD8+ T cells were significantly more abundant (p=0.001) but also a number of suppressive immune cells (M2 macrophages (p<0.001), regulatory T cells (p=0.005), myeloid-derived suppressor cells; MDSCs (p<0.001) (Figure 4B, Supplementary Figure S6). The gene discussed is CD8A; the disease is cancer.