Level of LAMP1 expression in ccRCC was associated with T stage (OR=0.569, T1-2 vs. T3-T4), M grade (OR=0.570, M0 vs. M1), clinicopathologic stage (OR=0.487, Stage I-II vs. Stage III-IV) and histological grade (OR=0.610, G1-2 vs. G3-4) were negatively correlated (P<0.05). This evidence concerns the gene LAMP1 and nonpapillary renal cell carcinoma.