Significantly differentially methylated 24-h oscillating genes enriched the following activated pathways: Xenobiotic Metabolism Signaling, Senescence Pathway, NRF2-mediated Oxidative Stress Response, Xenobiotic Metabolism General Signaling Pathway, Pulmonary Fibrosis Idiopathic Signaling Pathway, HIF1α Signaling, Xenobiotic Metabolism CAR Signaling Pathway, Neurotrophin/TRK Signaling, Autophagy. This evidence concerns the gene BDNF and pulmonary fibrosis.