According to Hong Z, et al., regulator of G-protein signaling 3 (RGS3) found miR-126-3 played an inhibitory role in regulating the activity of triple-negative breast cancer cells by targeting RGS3, suggest that miR-126-3p/RGS3 axis may be a potential therapeutic target for triple-negative breast cancer (35). Here, RGS3 is linked to triple-negative breast carcinoma.