Even though there is a possibility that the anti-inflammatory role of Kcnj8 against viral infection or LPS may be extrahematopoietic, effects within subsets of immune cells cannot be excluded given the expression pattern of Kcnj8 and Abcc9 in certain populations of immune cells, and the possible roles for KATP channels in macrophages (36, 37) and NK cells (40). The gene discussed is KCNJ8; the disease is viral infectious disease.