Moreover, statistical analyses of the evaluated blood markers and US findings for prediction of EM disease severity as judged and scored by laparoscopy defined high serum CA125 and NLR as the predictors of highest significance for differentiating patients who had severe EM (Stages III & IV) and regression analysis assured the high predictability of high NLR for that purpose. The gene discussed is MUC16; the disease is erythema multiforme.