A similar scenario was observed for RAP1GDS1, THPO, SOX17, and ATP8A2. For example, RAP1GDS1 is registered in OMIM with a T cell acute lymphocytic leukemia phenotype,15 but we analyzed it and published the data in the context of autosomal recessive syndromic intellectual disability.1 This evidence concerns the gene THPO and syndromic intellectual disability.