Analysis of data from the Cancer Cell Line Encyclopedia (CCLE) revealed that the expression levels of HMGCS1, HMGCR, IDI1, FDFT1, and SQLE were significantly higher in SCLC cell lines compared to non-small cell lung cancer (NSCLC) cell lines and other cancer cell lines (Figure 6A). Here, HMGCS1 is linked to small cell lung carcinoma.