Univariate analysis showed that RAB32 (HR = 2851, p < 0.001), age (HR = 1.665, p < 0.001), IDH mutation (HR = 0.336, p < 0.001), 1p19q (HR = 0.237, p < 0.001) and the chemotherapy (HR = 0.775, p = 0.011) was a prognostic factor for OS in glioma patients. Here, RAB32 is linked to central nervous system cancer.