IDH1 and central nervous system cancer: Similarly, multivariate analysis showed that RAB32 (HR = 1.735, p < 0.001), age (HR = 1.528, p < 0.001), IDH mutation (HR = 0.610, p < 0.001), and 1p19q were all absent (HR = 0.381, p < 0.001) and were prognostic factors for OS in glioma patients (Figure 3C, F).