GEO datasets showed that PPP1R14B had area under the curve (AUC) value > 0.95 that were more than known PCa-related genes AMACR and GDF15, displaying ideal predictive performance for PCa occurrence, as assessed by the ROC curves, and the nomogram models based on hub gene expression level further confirmed this point. This evidence concerns the gene GDF15 and posterior cortical atrophy.