ROC analysis indicated that PPP1R14B and two known PCa-related genes GDF15 and AMACR had AUC values > 0.8, with PPP1R14B having the largest AUC value (AUC, 0.972), AMACR the middle (AUC, 0.922) and GDF15 the smallest (AUC, 0.889) (Fig. 6b). Here, PPP1R14B is linked to posterior cortical atrophy.